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L. Salivarius Probiotic Powder 500 billion CFUs/gram (Refrigerated, Live Probiotic, No Fillers)
Histamine Free
Ingredients: Lactobacillus Salivarius (L. Salivarius)
NOTE: This is live bacteria and must be kept in the refrigerator.
DO NOT purchase no filler probiotic powder if it is NOT refrigerated. Fillers like maltodextrin, silicon dioxide, magnesium stearate, etc keep probiotics alive outside of the refrigerator (these fillers also cause a lot of digestive problems so we don't use them). The CFU count will be much lower than advertised for no filler powders that are not refrigerated.
We keep all our powders in the refrigerator before shipment. It will maintain potency for 5 weeks outside of the refrigerator so it will be ok when shipped to you.
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*Free international shipping over $100 USD (use code FREESHIPPING at checkout).
How do I measure this?
Two measuring spoons are included. The small spoon is 50 Billion CFU (0.1g) and the big spoon is 400 Billion CFU (0.8g).
Why powder and not capsules?
Our probiotic powder has no additives. Many people don't realize that a lot of additives worsen their symptoms. Additionally, the microbiome in your mouth, esophagus, and stomach are incredibly important to your health. Taking our flavorless probiotic powder keeps those areas healthy.
Why High Potency? How much should I take?
Using a dose less than 25 Billion per day will have limited health benefits -- you will need a higher potency to get desirable results. Many people have used other probiotic brands with minimal results because of their low potency.
It depends on the person and the issue that is being addressed. You’ll start to see results at a minimum of 25 Billion CFUs per day. The average daily dose by our customers is between 200-400 Billion CFUs per day. Some people see significant results with dosages as high as 800 Billion CFUs per day.
15 Gram Size ($2.99 per gram):
150 servings if using 50 Billion CFU serving size
50 Gram Size ($1.63 per gram)
6,000 servings if using 5 Billion CFU serving size (~1/256 teaspoon or 15.625mg)
3,000 servings if using 10 Billion CFU serving size (~1/128 teaspoon or 31.25mg)
1,500 servings if using 20 Billion CFU serving size (~1/64 teaspoon or 62.5mg)
750 servings if using 40 Billion CFU serving size (~1/32 teaspoon or 125mg)
400 servings if using 75 Billion CFU serving size (1/16 teaspoon or 0.25g)
200 servings if using 150 Billion CFU serving size (1/8 teaspoon or 0.5g)
100 servings if using 300 Billion CFU serving size (1/4 teaspoon or 1g)
100g Size ($1.33 per gram):
12,000 servings if using 5 Billion CFU serving size (~1/256 teaspoon or 15.625mg)
6,000 servings if using 10 Billion CFU serving size (~1/128 teaspoon or 31.25mg)
3,000 servings if using 20 Billion CFU serving size (~1/64 teaspoon or 62.5mg)
1,500 servings if using 40 Billion CFU serving size (~1/32 teaspoon or 125mg)
800 servings if using 75 Billion CFU serving size (1/16 teaspoon or 0.25g)
400 servings if using 150 Billion CFU serving size (1/8 teaspoon or 0.5g)
200 servings if using 300 Billion CFU serving size (1/4 teaspoon or 1g)
Statement on Allergens
Dairy Free
Sugar Free
Gluten Free
Preservative Free
Soy Free
GMO Free
Yeast Free
Casein Free
Free of Artificial Colors or Flavors
Prebiotic Free
How long will a 50 gram or 100 gram powder last?
50 grams will last about 2 months if you take 200 Billion CFUs per day or 8 months if you take 50 Billion CFUs per day. 100 grams will last about 4 months if you take 200 Billion CFUs per day.
Can infants and children take probiotics?
Based on existing research, infants can start taking probiotics at 6 months of age.
How much probiotics can an infant take?
Infants can take up to 50 Billion CFU per day.
What are CFUs?
CFU stands for Colony Forming Unit. This is the bacterial count of probiotics.
Why aren’t BulkProbiotics enteric coated?
Enteric coated probiotics are mainly a marketing gimmick. The strains that are used at BulkProbiotics are vetted to have excellent acid and bile tolerance as well as the capacity to survive intestinal transit.
What happens if I leave the probiotics outside of the refrigerator for a couple of days?
2 year temperature stability testing has been performed on our probiotics and the loss would be negligible. Our probiotics can remain at room temperature (or travel) for 5 weeks with limited loss, however, it is best to store the probiotics in the refrigerator for optimum potency.
Why do some individuals get a “die-off” reaction?
This is due to a ‘war’ that occurs between the probiotics and the bad bacteria in your body. If there is a large imbalance in your gut bacteria, the die-off reaction will be higher. To avoid this we recommend that you gradually increase your dosage starting with about 25 Billion CFU per day and increase every few days over a couple of weeks.
Do your probiotics contain any dairy or gluten?
Our probiotics are dairy and gluten free. They do not utilize milk, milk derivatives, GOS, or Inulin as additional ingredients in the fermentation media.
When should I take probiotics? Is it ok to take probiotics with drugs, vitamins, or antibiotics?
As a digestive aid, it is best to take 30 minutes before a meal; otherwise, it is also ok to take on an empty stomach in the morning or at bedtime (at least 2 hours after eating). Probiotics should not be taken with antibiotics (take 2 hours before or after taking antibiotics).
What is the return policy?
We accept returns within 30 days for all 10g probiotic powders that are unopened. We do not accept returns for any other sizes. The 10g size is available to experiment to help you find the right probiotic strains for you.
Lactobacillus salivarius, a bacterium that lives in the human mouth, has shown promise for dental health, weight management, immunity, skin health, and other potential benefits.
What is Lactobacillus salivarius?
Lactobacillus salivarius is one of the most prevalent species in human saliva. It produces organic acids, such as lactic acid and acetic acid, from carbohydrates, which can inhibit the growth of surrounding microorganisms. It also produces hydrogen peroxide and other antimicrobial substances [1].
This bacterium is believed to stimulate the immune system, improve intestinal disease and promote well-being [2].
Possibly Effective For
1) Dental Health
L. salivarius beneficially changed the bacterial population of gum plaque in 66 volunteers [3]
L. salivarius increased resistance to caries risk factors in 64 healthy volunteers [4].
Oral administration of L. salivarius improved bad breath, showed beneficial effects on bleeding on probing from the periodontal pocket, and inhibited the reproduction of “bad” bacteria [5, 6, 1, 7].
Periodontal clinical parameters especially improved in smokers [8].
However, the authors of one study suggested that L. salivarius itself may possess an inherent cariogenic activity following adherence to the tooth surface [9].
2) Obesity
L. salivarius increased the ratio of beneficial bacteria (Bacteroides, Prevotellae, and Porphyromonas) to Firmicutes-belonging bacteria in obese adolescents [10].
6-week supplementation of L. salivarius along with fructooligosaccharide (FOS) significantly reduced total cholesterol, “bad” (LDL) cholesterol, and triglycerides, and increased “good” (HDL) cholesterol in 45 human subjects. Blood inflammatory markers were also significantly reduced [11].
3) Immunity
Daily administration of L. salivarius to 40 healthy adults was safe and improved gut microbiota and different parameters related to immune response [12].
L. salivarius enhanced both innate and acquired immune responses in human cells [13].
4) Dermatitis
L. salivarius improved symptoms in children [14, 15], and adults with atopic dermatitis [16].
5) Mastitis
Oral administration of L. salivarius during late pregnancy prevented mastitis (breast infection) in 108 women [17].
6) Antibacterial Activity
L. salivarius produces a bacteriocin, an antimicrobial substance, that can significantly protect mice against infection with the invasive foodborne pathogen Listeria monocytogenes [18].
7) H. pylori
L. salivarius suppressed H. pylori and reduced infection-induced inflammatory responses in mice [19].
This inhibition is strain specific, though, and a study showed that only 9 out of the 28 L. salivarius strains tested inhibited H. pylori growth [20].
8) Gut Inflammation
L. salivarius facilitates the recovery of the inflamed tissue in rat colitis, by ameliorating the production of inflammatory mediators, such as cytokines, including TNF-α and NO [21].
9) Diabetes
Treating diabetic mice with dead L. salivarius reversed gut microbial imbalance, restored mucosal antibacterial protein and lessened endotoxin levels [22].
10) Liver Function
Pretreatment with L. salivarius improved acute liver injury in rats [23].
L. salivarius exerts a good health-promoting effect in acute liver failure [24].
11) Asthma
L. salivarius decreased the secretion of proinflammatory cytokines and showed beneficial immunomodulatory activity in blood cells drawn from asthmatic subjects [25].
L. salivarius decreased allergen-induced airway response in mice [26].
L. salivarius alleviated the clinical symptoms, airway hyperreactivity and airway inflammation in mice with asthma [27].
Mechanisms
In cell and animal studies, researchers have observed that L. salivarius:
- Reduced inflammatory markers such as hs-CRP, interleukins IL-6, IL-1β, TNFα and TGF-β [11, 25].
- Reduced elevated ALT, AST and total bilirubin [23].
- Increased IL-10 and /or IFNγ [23, 25].
- Improved the Th1/Th2 balance in asthma mice [27].
- Reduced eosinophil influx, IgE, and eotaxin in asthma [26].
*These statements have not been evaluated by the Food and Drug Administration.
*These products are not intended to diagnose, treat, cure, or prevent any disease.